Zipyran plus flavor for large dogs 1 tablet
Treatment of mixed infections by adult cestodes and nematodes / Antiparasitic for dogs
Zipyran Plus Sabor Perros Grandes Tablets / Antiparasitics
Praziquantel175 mgPyrantel (as pyrantel embonate)175 mgFebantel525 mg
Zipyran Plus Sabor Perros Grandes INDICATIONS
Treatment of mixed infections by adult cestodes and nematodes of the following species: - Nematodes: Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis-Cestodes: Echinococcus granulosus, Taenia hydatigena, Dipylidium caninum.
Zipyran Plus Sabor Perros Grandes PROPERTIES
Praziquantel is an anthelmintic effective against a number of cestodes. It causes severe damage to the parasite integument, making it more permeable to the excessive loss of glucose and facilitating the attack of the proteolytic enzymes. At the same time, it acts on the motility and the “anchoring” organs of the cestode, inducing a spastic paralysis.The active metabolites of Febantel act via inhibition of tubulin within the parasite, thus resulting in disruption of structures vital to the normal functioning of the helminth. Glucose uptake, in particular is affected, leading to a depletion in cell ATP. The parasite dies upon exhaustion of its energy reserves Pyrantel acts as a cholinergic agonist, inducing a spastic paralysis of the nematodes and thereby allowing removal from the gastro- intestinal (GI) system by peristalsis.
Zipyran Plus Sabor Perros Grandes CONTRAINDICATIONS
Do not administer to extremely debilitated animals.Do not use in cases of hypersensitivity to the active substance or to any of the excipients.Do not use simultaneously with piperazine.
Zipyran Plus Sabor Perros Grandes POSOLOGY
For single oral treatment only. The recommended dose is 5 mg of Praziquantel, 5 mg of Pyrantel (as embonate) and 15 mg of Febantel per kg of body weight (equivalent to one tablet/35 kg bw).
Veterinarian prescription: Yes