Program 400 for dogs between 20 and 80 kg 6 tablets
Prevention and lasting control of flea infestation in dogs
Program Tablets 409.8mg
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Active ingredient mg/tablet
Ferric Oxide Brown (E172) 0.0448
Titanium dioxide (E171) 6.6911
For a full list of excipients see section 6.1
3. PHARMACEUTICAL FORM
White, round biconvex tablets
4. CLINICAL PARTICULARS
4.1 Target Species
4.2 Indications for use
For the prevention and lasting control of flea infestation in dogs. Effective against the dominant flea species Ctenocephalides felis and C. canis.
4.4 Special warnings for each target species
4.5 Special precautions for use
i) Special precautions for use in animals
Use only in weaned puppies.
If signs of flea infestation or disease persist or appear, consult your veterinary surgeon.
ii) Special precautions to be taken by the person administering the medicinal product to animals
Wash hands after use.
4.6 Adverse reactions (frequency and seriousness)
On very rare occasions, nervous signs, itching, vomiting or diarrhoea have been reported in dogs following treatment with Program Tablets.
4.7 Use during pregnancy, lactation or lay
Can be used during pregnancy and lactation.
4.8 Interaction with other medicinal products and other forms of interaction
4.9 Amounts to be administered and administration route
The minimum recommended dose rate is 10mg/ai/kg/month.
Recommended monthly dose:
Dog weight – 21 kg to 40 kg = 1 tablet
Dog weight – 41 kg to 80 kg = 2 tablets
In order to avoid under-dosing in growing puppies, they should be weighed each month prior to dosing.
To be fully effective the tablets must be administered together with food, e.g. added to a portion of the daily food, hidden in pieces of meat, etc. or administered by mouth after feeding. After administration, the dog should be watched for several minutes to ensure that the whole dose has been swallowed.
To prevent flea infestations the product should be administered at monthly intervals for at least six months during the flea season, starting two months before fleas become active.
If the dog is already infested with fleas, no viable flea eggs are produced from 24 hours after the first administration. The speed of elimination of a pre-existing infestation is dependant upon the number of flea larvae and pupae in the environment when treatment starts and the climatic conditions.
Program does not kill adult fleas. The product works by preventing the development of flea larvae. If dogs have a high level of flea infestation at the start of the treatment, it is necessary to apply a product that is recommended for use against adult fleas during the first one to two months, or longer depending on the environmental challenge.
It is essential that all dogs and all cats (except unweaned puppies and kittens) living in a household are treated to stop flea reproduction.
For cats use Program Suspension.
4.10 Overdose (symptoms, emergency procedures and antidotes) if necessary
4.11 Withdrawal period(s)
5. PHARMACOLOGICAL PROPERTIES
Lufenuron is an insect growth regulator belonging to the benzolyurea group which acts by interfering with the normal synthesis, polymerisation and deposition of chitin.
5.1 Pharmacodynamic properties
ATC vet code: QP53BC01
Fleas take up the active ingredient through the blood and transfer it to their eggs. The formulation of larval chitin structures, a process typical to insects is blocked and the development of their numerous offspring is stopped. A new infestation of the home with fleas is prevented.
Fleas picked up by the dog outside the home environment are prevented from causing a new infestation of the home.
5.2 Pharmacokinetic particulars
After administering orally to the dog, the active ingredient is quickly absorbed. Sufficient absorption is only achieved if administered on a full stomach. The low excretion rate ensures an effective concentration of the active ingredient in the blood for one month.
6. PHARMACEUTICAL PECULIARS
6.1 List of excipients
Macrogol 8000 Lactose monohydrate Cellulose Microcrystalline Pregelatinised starch Croscarmellose sodium Magnesium stearate
Titanium dioxide Ferric oxide, brown Hypromellose Macrogol 8000 Purified talc
Shelf-life of the veterinary medicinal product as packaged for sale: 5 years
6.4 Special precautions for storage
Store in a dry place.
Protect from light.