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Bayer
Advantix spot-on solution for dogs up to 4 kg 4 pipettes

Treatment and prevention of flea infestation and biting lice in dogs

Prescription required* (Exceptions apply)

Advantix Spot-on is a clear yellowish to brownish Spot-on solution for dogs.

Each Advantix Spot-on pipette contains:

  • Active substances:
Trade name Pipette size Imidacloprid Permethrin Butylhydroxytoluene E321
Advantix Spot-on for dogs up to 4 kg 0.4 ml 40 mg 200 mg 0.4 mg
Advantix Spot-on for dogs over 4 kg up to 10 kg 1 ml 100 mg 500 mg 1 mg
Advantix Spot-on for dogs over 10 kg up to 25 kg 2.5 ml 250 mg 1250 mg 2.5 mg
Advantix Spot-on for dogs over 25 kg up to 40 kg 4 ml 400 mg 2000 mg 4 mg
  • List of excipients:
    • Butylhydroxytoluene (E321)
    • N-Methylpyrrolidone
    • Miglyol 812
    • Citric acid (E330)

Indications for use of Advantix Spot-on, specifying the target species:

  • For the treatment and prevention of flea (Ctenocephalides canis, Ctenocephalides felis) infestation.

  • Fleas on dogs are killed within one day following treatment. One treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).

  • For the treatment of biting lice (Trichodectes canis).

  • The product has persistent acaricidal and repellent efficacy against tick infestations (Rhipicephalus sanguineus and Ixodes ricinus for four weeks, and Dermacentor reticulatus for three weeks).

  • By repelling and killing the tick vector Rhipicephalus sanguineus, the product reduces the likelihood of transmission of the pathogen Ehrlichia canis, thereby reducing the risk of canine ehrlichiosis. The reduction in risk has been shown in studies to commence from 3 days following application of the product and to persist for 4 weeks.

  • Ticks already on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore the removal of ticks already on the dog at the time of treatment is recommended, in order to prevent them from attaching and having a blood meal.

  • One treatment provides repellent (anti-feeding) activity against sand flies (Phlebotomus papatasi for two weeks and Phlebotomus perniciosus for three weeks), against mosquitoes (Aedes aegypti for two weeks and Culex pipiens for four weeks) and against stable flies (Stomoxys calcitrans) for four weeks.

  • In the absence of available data the product should not be used on puppies of less than 7 weeks of age or 1.5 kg of weight.

  • Do not use in case of hypersensitivity to the active substances or to any of the excipients.

  • Do not use on cats. (Refer to section 4.5 – Special precautions for use).

Advantix Spot-on amounts to be administered and administration route:

  • The recommended minimum dose is: 10 mg/kg body weight (bw) imidacloprid and 50 mg/kg body weight (bw) permethrin.
  • Dosing Scheme for Advantix Spot-on:
Trade name Pipette size Imidacloprid (mg/kg body weight) Permethrin (mg/kg body weight)
Advantix Spot-on for dogs up to 4 kg 0.4 ml Minimum 10 Minimum of 50
Advantix Spot-on for dogs over 4 kg up to 10 kg 1 ml 10 - 25 50 - 125
Advantix Spot-on for dogs over 10 kg up to 25 kg 2.5 ml 10 - 25 50 - 125
Advantix Spot-on for dogs over 25 kg up to 40 kg 4 ml 10 - 16 50 - 80
  • For dogs > 40 kg the appropriate combination of pipettes should be used.
  • To reduce re-infestation from emergence of new fleas, it is recommended to treat all dogs in a household. Other animals living in the same household should also be treated with a suitable product. To aid further in reducing environmental challenge, the additional use of a suitable environmental treatment against adult fleas and their developmental stages is recommended.
  • The product remains effective if the animal becomes wet. However, prolonged, intense exposure to water should be avoided. In cases of frequent water exposure the persistent efficacy may be reduced. In these cases do not retreat more frequently than once weekly. If a dog requires a shampoo, it should be administered before applying Advantix or at least 2 weeks after application, to optimise efficacy of the product.
  • In case of biting louse infestation, a further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.
  • For dermal use only. Apply only to undamaged skin.
    • Remove one pipette from the package. Hold applicator pipette in an upright position, twist and pull cap off. Turn the cap around and place the other end of cap back on pipette. Twist cap to break seal, then remove cap from pipette.
    • For dogs 10 kg body weight or less: With the dog standing still, part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin.
    • For dogs of more than 10 kg body weight: With the dog standing still, the entire contents of the Advantix pipette should be applied evenly to four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the pipette on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.

Advantix Spot-on is a clear yellowish to brownish Spot-on solution for dogs.

Each Advantix Spot-on pipette contains:

  • Active substances:
Trade name Pipette size Imidacloprid Permethrin Butylhydroxytoluene E321
Advantix Spot-on for dogs up to 4 kg 0.4 ml 40 mg 200 mg 0.4 mg
Advantix Spot-on for dogs over 4 kg up to 10 kg 1 ml 100 mg 500 mg 1 mg
Advantix Spot-on for dogs over 10 kg up to 25 kg 2.5 ml 250 mg 1250 mg 2.5 mg
Advantix Spot-on for dogs over 25 kg up to 40 kg 4 ml 400 mg 2000 mg 4 mg
  • List of excipients:
    • Butylhydroxytoluene (E321)
    • N-Methylpyrrolidone
    • Miglyol 812
    • Citric acid (E330)

Indications for use of Advantix Spot-on, specifying the target species:

  • For the treatment and prevention of flea (Ctenocephalides canis, Ctenocephalides felis) infestation.

  • Fleas on dogs are killed within one day following treatment. One treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).

  • For the treatment of biting lice (Trichodectes canis).

  • The product has persistent acaricidal and repellent efficacy against tick infestations (Rhipicephalus sanguineus and Ixodes ricinus for four weeks, and Dermacentor reticulatus for three weeks).

  • By repelling and killing the tick vector Rhipicephalus sanguineus, the product reduces the likelihood of transmission of the pathogen Ehrlichia canis, thereby reducing the risk of canine ehrlichiosis. The reduction in risk has been shown in studies to commence from 3 days following application of the product and to persist for 4 weeks.

  • Ticks already on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore the removal of ticks already on the dog at the time of treatment is recommended, in order to prevent them from attaching and having a blood meal.

  • One treatment provides repellent (anti-feeding) activity against sand flies (Phlebotomus papatasi for two weeks and Phlebotomus perniciosus for three weeks), against mosquitoes (Aedes aegypti for two weeks and Culex pipiens for four weeks) and against stable flies (Stomoxys calcitrans) for four weeks.

  • In the absence of available data the product should not be used on puppies of less than 7 weeks of age or 1.5 kg of weight.

  • Do not use in case of hypersensitivity to the active substances or to any of the excipients.

  • Do not use on cats. (Refer to section 4.5 – Special precautions for use).

Advantix Spot-on amounts to be administered and administration route:

  • The recommended minimum dose is: 10 mg/kg body weight (bw) imidacloprid and 50 mg/kg body weight (bw) permethrin.
  • Dosing Scheme for Advantix Spot-on:
Trade name Pipette size Imidacloprid (mg/kg body weight) Permethrin (mg/kg body weight)
Advantix Spot-on for dogs up to 4 kg 0.4 ml Minimum 10 Minimum of 50
Advantix Spot-on for dogs over 4 kg up to 10 kg 1 ml 10 - 25 50 - 125
Advantix Spot-on for dogs over 10 kg up to 25 kg 2.5 ml 10 - 25 50 - 125
Advantix Spot-on for dogs over 25 kg up to 40 kg 4 ml 10 - 16 50 - 80
  • For dogs > 40 kg the appropriate combination of pipettes should be used.
  • To reduce re-infestation from emergence of new fleas, it is recommended to treat all dogs in a household. Other animals living in the same household should also be treated with a suitable product. To aid further in reducing environmental challenge, the additional use of a suitable environmental treatment against adult fleas and their developmental stages is recommended.
  • The product remains effective if the animal becomes wet. However, prolonged, intense exposure to water should be avoided. In cases of frequent water exposure the persistent efficacy may be reduced. In these cases do not retreat more frequently than once weekly. If a dog requires a shampoo, it should be administered before applying Advantix or at least 2 weeks after application, to optimise efficacy of the product.
  • In case of biting louse infestation, a further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.
  • For dermal use only. Apply only to undamaged skin.
    • Remove one pipette from the package. Hold applicator pipette in an upright position, twist and pull cap off. Turn the cap around and place the other end of cap back on pipette. Twist cap to break seal, then remove cap from pipette.
    • For dogs 10 kg body weight or less: With the dog standing still, part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin.
    • For dogs of more than 10 kg body weight: With the dog standing still, the entire contents of the Advantix pipette should be applied evenly to four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the pipette on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.
39.80
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on Wednesday 8 April
AIR FREIGHT

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