Zoetis
Excenel flow 50 mg/ml - suspension for injection cattle and pigs - 100 ml

Treatment of bacterial respiratory disease in cattle and pigs

Prescription required* (Exceptions apply)

Excenel Flow is an opaque, white to off-white suspension for injection for cattle and pigs.

Each Excenel Flow ml contains:

  • Active substance:

    • Ceftiofur (as hydrochloride) 50.0 mg
  • List of excipients:

    • Polysorbate 80
    • Triglycerides Medium-chain
    • Water for injections

Indications for use of Excenel Flow, specifying the target species:

  • Infections associated with bacteria sensitive to ceftiofur:
  • Pigs:
    • For the treatment of bacterial respiratory disease associated with Pasteurella multocida, Actinobacillus pleuropneumoniae and Streptococcus suis.
  • Cattle:
    • For the treatment of bacterial respiratory disease associated with Mannheimia haemolytica (former Pasteurella haemolytica), Pasteurella multocida and Histophilus somni (former Haemophilus somnus).
    • For the treatment of acute interdigital necrobacillosis (panaritium, foot rot), associated with Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica). For treatment of the bacterial component of acute post-partum (puerperal) metritis within 10 days after calving associated with Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum, sensitive to ceftiofur, were treatment with another antimicrobial has failed. Do not administer to an animal previously found to be hypersensitive to ceftiofur and other β -lactam antibiotics.
  • Do not inject intravenously.
  • Do not use in cases where resistance to other cephalosporins or beta-lactam antibiotics has occurred.
  • Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance to humans.

Excenel Flow Withdrawal period:

  • Pigs: meat and offal: 2 days.
  • Cattle: meat and offal: 6 days; milk: zero hours.

Amounts of Excenel Flow to be administered and administration route:

  • Before use, shake the bottle vigorously for a maximum of 60 seconds or until the product appears adequately resuspended.
  • To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
  • Subsequent injections must be given at different sites.
  • 50 ml and 100 ml vials can be broached a maximum of 50 times. 250 ml vials can be broached a maximum of 33 times. Otherwise, the use of a multiple-dose syringe is recommended.
  • Pigs:
    • 3 mg ceftiofur /kg bw/day for 3 days via intramuscular route, i.e. 1 ml/16 kg bw at each injection.
    • Not more than 4 ml should be administered per injection site.
  • Cattle:
    • Respiratory disease: 1 mg ceftiofur /kg bw/day for 3 to 5 days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection.
    • Acute interdigital necrobacillosis: 1 mg/kg bw/day for 3 days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection.
    • Acute post-partum metritis within 10 days after calving: 1 mg/kg bw/day for 5 consecutive days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection. In case of acute post-partum metritis, additional supportive therapy might be required in some cases.
    • Not more than 13 ml should be administered per injection site.

Excenel Flow is an opaque, white to off-white suspension for injection for cattle and pigs.

Each Excenel Flow ml contains:

  • Active substance:

    • Ceftiofur (as hydrochloride) 50.0 mg
  • List of excipients:

    • Polysorbate 80
    • Triglycerides Medium-chain
    • Water for injections

Indications for use of Excenel Flow, specifying the target species:

  • Infections associated with bacteria sensitive to ceftiofur:
  • Pigs:
    • For the treatment of bacterial respiratory disease associated with Pasteurella multocida, Actinobacillus pleuropneumoniae and Streptococcus suis.
  • Cattle:
    • For the treatment of bacterial respiratory disease associated with Mannheimia haemolytica (former Pasteurella haemolytica), Pasteurella multocida and Histophilus somni (former Haemophilus somnus).
    • For the treatment of acute interdigital necrobacillosis (panaritium, foot rot), associated with Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica). For treatment of the bacterial component of acute post-partum (puerperal) metritis within 10 days after calving associated with Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum, sensitive to ceftiofur, were treatment with another antimicrobial has failed. Do not administer to an animal previously found to be hypersensitive to ceftiofur and other β -lactam antibiotics.
  • Do not inject intravenously.
  • Do not use in cases where resistance to other cephalosporins or beta-lactam antibiotics has occurred.
  • Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance to humans.

Excenel Flow Withdrawal period:

  • Pigs: meat and offal: 2 days.
  • Cattle: meat and offal: 6 days; milk: zero hours.

Amounts of Excenel Flow to be administered and administration route:

  • Before use, shake the bottle vigorously for a maximum of 60 seconds or until the product appears adequately resuspended.
  • To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
  • Subsequent injections must be given at different sites.
  • 50 ml and 100 ml vials can be broached a maximum of 50 times. 250 ml vials can be broached a maximum of 33 times. Otherwise, the use of a multiple-dose syringe is recommended.
  • Pigs:
    • 3 mg ceftiofur /kg bw/day for 3 days via intramuscular route, i.e. 1 ml/16 kg bw at each injection.
    • Not more than 4 ml should be administered per injection site.
  • Cattle:
    • Respiratory disease: 1 mg ceftiofur /kg bw/day for 3 to 5 days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection.
    • Acute interdigital necrobacillosis: 1 mg/kg bw/day for 3 days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection.
    • Acute post-partum metritis within 10 days after calving: 1 mg/kg bw/day for 5 consecutive days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection. In case of acute post-partum metritis, additional supportive therapy might be required in some cases.
    • Not more than 13 ml should be administered per injection site.
49.30
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on Tuesday 26 November
AIR FREIGHT

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