MSD
Nuflor 300 mg/ml solution for injection for cattle and sheep 50 ml

Treatment of respiratory tract infections in cattle and sheeps

Prescription required* (Exceptions apply)

Nuflor 300 mg/ml is a clear, light yellow to straw-coloured, somewhat viscous solution for injection for:

Cattle:

  • Diseases caused by florfenicol susceptible bacteria.
  • Metaphylactic and therapeutic treatment of respiratory tract infections in cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. The presence of the disease in the herd should be established before metaphylactic treatment.

Sheep:

  • Treatment of ovine respiratory tract infections due to Mannheimia haemolytica and Pasteurella multocida susceptible to florfenicol.

Each ml of Nuflor 300 mg/ml contains:

Active substance:

  • Florfenicol 300 mg

Excipients:

  • N-methyl-2-pyrollidone
  • Propylene glycol
  • Macrogol 300

Nuflor 300 mg/ml:

  • Do not use in adult bulls and rams intended for breeding purposes.
  • Do not use in the case of known hypersensitivity to the active substance or to any of the excipients.

Nuflor 300 mg/ml posology:

  • Swab septum before removing each dose. Use a dry sterile needle and syringe. To ensure a correct dosage body weight should be determined as accurately as possible to avoid underdosing.
  • The vials should not be broached more than 20 times. User should therefore select the most appropriate vial size according to the target species to be treated. When treating groups of animals at the same time, use of a draw-off needle in the vial stopper is recommended to avoid excess stopper broaching. The draw-off needle should be removed after treatment.
  • For treatment:
    • Cattle: Intramuscular use: 20 mg/kg bodyweight (1 ml/15 kg) to be administered twice 48 hours apart using a 16 gauge needle. Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only using a 16 gauge needle. The dose volume given at any one injection site should not exceed 10 ml. The injection should only be given in the neck.
    • Sheep: Intramuscular use: 20 mg florfenicol/kg bodyweight (1 ml/15 kg) to be administered daily for three consecutive days. The volume administered per injection site should not exceed 4 ml. Pharmacokinetic studies showed that mean plasma concentrations remain above MIC90 (1 μg/ml) for up to 18 hours after administration of the product at the recommended treatment dose. The pre-clinical data supported the recommended treatment interval (24 hours) for target pathogens with MIC up to 1 μg/ml.
  • For metaphylaxis:
    • Cattle: Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only using a 16 gauge needle. The dose volume given at any one injection site should not exceed 10 ml. The injection should only be given in the neck.

Nuflor 300 mg/ml is a clear, light yellow to straw-coloured, somewhat viscous solution for injection for:

Cattle:

  • Diseases caused by florfenicol susceptible bacteria.
  • Metaphylactic and therapeutic treatment of respiratory tract infections in cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. The presence of the disease in the herd should be established before metaphylactic treatment.

Sheep:

  • Treatment of ovine respiratory tract infections due to Mannheimia haemolytica and Pasteurella multocida susceptible to florfenicol.

Each ml of Nuflor 300 mg/ml contains:

Active substance:

  • Florfenicol 300 mg

Excipients:

  • N-methyl-2-pyrollidone
  • Propylene glycol
  • Macrogol 300

Nuflor 300 mg/ml:

  • Do not use in adult bulls and rams intended for breeding purposes.
  • Do not use in the case of known hypersensitivity to the active substance or to any of the excipients.

Nuflor 300 mg/ml posology:

  • Swab septum before removing each dose. Use a dry sterile needle and syringe. To ensure a correct dosage body weight should be determined as accurately as possible to avoid underdosing.
  • The vials should not be broached more than 20 times. User should therefore select the most appropriate vial size according to the target species to be treated. When treating groups of animals at the same time, use of a draw-off needle in the vial stopper is recommended to avoid excess stopper broaching. The draw-off needle should be removed after treatment.
  • For treatment:
    • Cattle: Intramuscular use: 20 mg/kg bodyweight (1 ml/15 kg) to be administered twice 48 hours apart using a 16 gauge needle. Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only using a 16 gauge needle. The dose volume given at any one injection site should not exceed 10 ml. The injection should only be given in the neck.
    • Sheep: Intramuscular use: 20 mg florfenicol/kg bodyweight (1 ml/15 kg) to be administered daily for three consecutive days. The volume administered per injection site should not exceed 4 ml. Pharmacokinetic studies showed that mean plasma concentrations remain above MIC90 (1 μg/ml) for up to 18 hours after administration of the product at the recommended treatment dose. The pre-clinical data supported the recommended treatment interval (24 hours) for target pathogens with MIC up to 1 μg/ml.
  • For metaphylaxis:
    • Cattle: Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only using a 16 gauge needle. The dose volume given at any one injection site should not exceed 10 ml. The injection should only be given in the neck.

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