MSD
Engemycin solution for injection for cattle, sheep, pigs and horses 100 ml

For the treatment of infections caused by organisms sensitive in horses, cattle, sheeps and pigs

This drug is unauthorized in certain countries
Prescription required* (Exceptions apply)

Engemycin 10 % is a solution for injection used in cattle, sheep, pigs and horses to treat infections caused by organisms sensitive to oxytetracycline such as:

  • Streptococcus spp.
  • Staphylococcus spp.
  • L. monocytogenes
  • P. haemolytica
  • H. parahaemolyticus and
  • B. bronchiseptica and against
  • Chlamydophila abortus, the causative organism of enzootic abortion in sheep.

One ml Engemycin 10 % of contains:

Active substance:

  • Oxytetracycline (as hydrochloride) 100 mg

Excipients:

  • Sodium formaldehyde sulphoxylate 5 mg
  • Magnesium Oxide
  • Povidone K12
  • Ethonolamine
  • Water for injection

Engemycin 10 %:

  • Must not be administered to horses during concomitant therapy with corticosteroids.

Withdrawal periods:

  • 24 hour dose:
    • Milk Cows: 6 days
    • Cattle: 35 days
    • Sheep: 14 days
    • Pigs: 14 days
  • Prolonged action dose:
    • Milk Cows 6 days
    • Cattle 21 days
    • Sheep 14 days
    • Pigs 10 days
  • Not for use in horses intended for human consumption.
  • Not for use in sheep producing milk for human consumption.
  • Treated horses may never be slaughtered for human consumption
  • The horses must have been declared as not intended for human consumption under national horse passport legislation.

Engemycin 10 % posology:

  • Can be administered at either a low dose rate for a 24 hour duration of activity or at a high dose rate for prolonged duration of activity.
  • 24 hour dosage regime: The recommended dosage rate is 3-10 mg/kg bodyweight (depending on age and species - see table) by intramuscular or intravenous injection. The treatment may be repeated at 24 hour intervals up to 4 times (5 treatments in all). Intravenous injections must be given slowly over a period of at least one minute.
Animal Weight kg Dose mg/kg Volume ml
Horse 500 5 25
Foal 100 10 10
Cow 500 3 15
Calf 100 8 8
Sow/boar 150 5 7.5
Pig 25 8 2
Sheep 50 8 4
Lamb 25 8 2
  • Prolonged action dosage regime: 10 or 20 mg/kg bodyweight depending on age and species (see table) by intramuscular injection only, repeated once after 48-60 hours if required. This dosage regime is not advised for use in horses.
Animal Weight kg Dose mg/kg Volume ml
Horse Not recommended
Foal Not recommended
Cow 500 10 50
Calf 100 20 20
Sow/boar 150 10 15
Pig 25 20 5
Sheep 50 20 10
Lamb 25 20 5
  • Prophylactic treatment of enzootic abortion in sheep: 20 mg/kg administered about day 95-100 of gestation. A further treatment may be given 2-3 weeks later.
  • Before administration, clean the area of the injection site and swab with spirit.
  • Repeat doses should be administered at different sites, and the sites massaged well after injection.
  • Maximum recommended dose at any one site: 20 ml for cattle, 10 ml for sheep and pigs.

Engemycin 10 % is a solution for injection used in cattle, sheep, pigs and horses to treat infections caused by organisms sensitive to oxytetracycline such as:

  • Streptococcus spp.
  • Staphylococcus spp.
  • L. monocytogenes
  • P. haemolytica
  • H. parahaemolyticus and
  • B. bronchiseptica and against
  • Chlamydophila abortus, the causative organism of enzootic abortion in sheep.

One ml Engemycin 10 % of contains:

Active substance:

  • Oxytetracycline (as hydrochloride) 100 mg

Excipients:

  • Sodium formaldehyde sulphoxylate 5 mg
  • Magnesium Oxide
  • Povidone K12
  • Ethonolamine
  • Water for injection

Engemycin 10 %:

  • Must not be administered to horses during concomitant therapy with corticosteroids.

Withdrawal periods:

  • 24 hour dose:
    • Milk Cows: 6 days
    • Cattle: 35 days
    • Sheep: 14 days
    • Pigs: 14 days
  • Prolonged action dose:
    • Milk Cows 6 days
    • Cattle 21 days
    • Sheep 14 days
    • Pigs 10 days
  • Not for use in horses intended for human consumption.
  • Not for use in sheep producing milk for human consumption.
  • Treated horses may never be slaughtered for human consumption
  • The horses must have been declared as not intended for human consumption under national horse passport legislation.

Engemycin 10 % posology:

  • Can be administered at either a low dose rate for a 24 hour duration of activity or at a high dose rate for prolonged duration of activity.
  • 24 hour dosage regime: The recommended dosage rate is 3-10 mg/kg bodyweight (depending on age and species - see table) by intramuscular or intravenous injection. The treatment may be repeated at 24 hour intervals up to 4 times (5 treatments in all). Intravenous injections must be given slowly over a period of at least one minute.
Animal Weight kg Dose mg/kg Volume ml
Horse 500 5 25
Foal 100 10 10
Cow 500 3 15
Calf 100 8 8
Sow/boar 150 5 7.5
Pig 25 8 2
Sheep 50 8 4
Lamb 25 8 2
  • Prolonged action dosage regime: 10 or 20 mg/kg bodyweight depending on age and species (see table) by intramuscular injection only, repeated once after 48-60 hours if required. This dosage regime is not advised for use in horses.
Animal Weight kg Dose mg/kg Volume ml
Horse Not recommended
Foal Not recommended
Cow 500 10 50
Calf 100 20 20
Sow/boar 150 10 15
Pig 25 20 5
Sheep 50 20 10
Lamb 25 20 5
  • Prophylactic treatment of enzootic abortion in sheep: 20 mg/kg administered about day 95-100 of gestation. A further treatment may be given 2-3 weeks later.
  • Before administration, clean the area of the injection site and swab with spirit.
  • Repeat doses should be administered at different sites, and the sites massaged well after injection.
  • Maximum recommended dose at any one site: 20 ml for cattle, 10 ml for sheep and pigs.

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